Small NBL Dataset for Analysis of AKT Signaling

ExpressionData.csv ---------------------------- A small subset of transcriptomics data (30 genes) curated for learning Gene Regulatory Networks (GRNs) pertaining to signaling by the ALK pathway. Genes were selected by referencing the "signaling by ALK" pathway from Reactome (https://reactome.org/content/detail/R-HSA-201556). This subset of data belongs the TARGET-NBL project (https://portal.gdc.cancer.gov/projects/TARGET-NBL), hosted via the Genomic Data Commons Data Portal (https://portal.gdc.cancer.gov/). Please refer to GDCs data access policies (https://gdc.cancer.gov/about-gdc/gdc-policies) if planning to use the data. refNetwork.csv ---------------------- Contains a reference network of known pairwise regulatory relationships among the genes of which we have transcriptomics data available in "ExpressionData.csv." These relationships were again determined by referencing the "signaling by ALK" pathway from Reactome (https://reactome.org/content/detail/R-HSA-201556).ExpressionData.csv —— 该文件为经人工整理的小型转录组学数据子集（包含30个基因），专为学习ALK通路信号传导相关的基因调控网络（Gene Regulatory Networks，GRNs）而构建。基因筛选参考自Reactome数据库的"ALK通路信号传导"通路（https://reactome.org/content/detail/R-HSA-201556）。该数据集子集隶属于TARGET-NBL项目（https://portal.gdc.cancer.gov/projects/TARGET-NBL），由基因组数据共享数据门户（https://portal.gdc.cancer.gov/）托管。若计划使用该数据，请参阅GDC数据访问政策（https://gdc.cancer.gov/about-gdc/gdc-policies）。 refNetwork.csv —— 该文件包含已知的成对基因调控关系参考网络，所涉基因均为ExpressionData.csv中收录的转录组学数据覆盖的基因。上述调控关系同样参考自Reactome数据库的"ALK通路信号传导"通路（https://reactome.org/content/detail/R-HSA-201556）。