For the paper "Systematic discovery of Type V CRISPR-Cas systems expands the functional and evolutionary diversity of RNA-guided nucleases." Contains DNA-sequencing reads containing repeat-spacer-repe
We investigated whether GATA2 enhancer-driven transcription of EVI1 in inv(3)/t(3;3) is reversible in leukemia cells. In primary inv(3)/t(3;3) AML, immature CD34+CD15- cells can be discriminated from
CRISPR (clustered regularly interspaced short palindromic repeat) systems mediate adaptive immunity in diverse prokaryotes. CRISPR-associated Cas1 and Cas2 proteins have been shown to enable adaptatio