Scoring of docking solutions at the rigid body stage of the CPORT docking runs.

The table indicates the percentage of cases for which at least one correct structure is selected in the top 400, and the percentage of complexes of which the number of correct structures is higher than random selection (enrichment) or lower than random selection (depletion). Significance (pOne-star and two-star criteria correspond to the CAPRI [18] definitions (see Material & Methods). For one-star structures, only those complexes are considered with at least 10 one-star solutions among the 10 000 (63% of all complexes). For two-star structures, only those complexes are considered with at least one two-star solution (44% of all complexes). The fnat criterion is not taken into account.