Significantly different pathways comparing glucosamine and chondroitin supplementation to placebo via gene-set enrichment analysis in Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) databases (n = 18).

1 Among the total number of genes in the pathway, number of unique genes in our array data2 Total number of corresponding antibody probes in the assay3 Among the significant probes, via paired t-test comparing G&C to placebo, the number that have an effect size >04 Among the significant probes, via paired t-test comparing G&C to placebo, the number that have an effect size 5 GO = Gene Ontology; KEGG = Kyoto Encyclopedia of Genes and Genomes*All pathways listed were statistically significant with Bonferroni correction (P -4 for KEGG pathway; P-5 for GO pathway)Significantly different pathways comparing glucosamine and chondroitin supplementation to placebo via gene-set enrichment analysis in Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) databases (n = 18).