Integrated Genomic, Functional and Prognostic Characterization of atypical Chronic Myeloid Leukemia
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA604582
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资源简介：
Atypical chronic myeloid leukemia (aCML) is a rare BCR-ABL1 negative clonal disorder, which belongs to the myelodysplastic/myeloproliferative group. This disease is characterized by recurrent somatic mutations in SETBP1, ASXL1 and ETNK1 genes, as well as high genetic heterogeneity, thus posing a great therapeutic challenge. With the aim to provide a comprehensive genomic characterization of aCML we applied a high-throughput sequencing strategy to 43 aCML samples, including both whole-exome and RNA-sequencing data.
创建时间：
2020-02-03
