Codelists for "Systemic Therapies for Psoriatic Disease and Major Adverse Cardiovascular Events in Older Adults: A Population-based Cohort Study"

This repository provides diagnosis, procedure, and medication codelists (including Drug Identification Numbers, DINs) used in the study "Systemic therapies for psoriatic disease and major adverse cardiovascular events in older adults: a population-based cohort study." The codelists support transparent and reproducible definitions of: Study population with psoriatic disease (psoriasis and psoriatic arthritis) Exposure to systemic psoriatic therapies (DIN-based drug classes) Major adverse cardiovascular events (MACE) outcome and its individual components Exclusion criteria Covariables including comorbidities and medication-based covariables We developed those codelists for use with Ontario administrative health data holdings at ICES, including databases maintained by the Canadian Institute for Health Information (CIHI), the Ontario Drug Benefit Database (ODB), the Ontario Health Insurance Plan Claims Database (OHIP), and the Canadian Organ Replacement Register (CORR). This repository contains codelists and DIN lists only. It does not include individual-level data or analytic code. Data sharing agreements prohibit public release of the underlying administrative data. Access to ICES-held data may be requested through ICES Data & Analytic Services (https://www.ices.on.ca/DAS). More detailed file descriptions are available in README.md in the repository root (codelists/). We provide variable algorithms (including lookback windows and operational definitions) in the supplement of the corresponding article. Please cite the corresponding article and this Zenodo record.本仓库提供了研究《老年人群银屑病性疾病全身治疗与主要不良心血管事件：一项基于人群的队列研究》中所使用的诊断、操作与药物编码列表（含药物识别码（Drug Identification Numbers，DIN））。 该编码列表可支撑以下内容的透明化、可复现定义： - 银屑病性疾病（银屑病与银屑病关节炎）研究队列人群 - 银屑病全身治疗暴露情况（基于DIN的药物类别） - 主要不良心血管事件（Major Adverse Cardiovascular Events, MACE）结局及其各独立组成成分 - 排除标准 - 混杂变量，包括合并症与基于药物的混杂变量 本团队开发上述编码列表，用于处理安大略省计算健康科学研究所（ICES）所持有的行政健康数据集，涵盖加拿大卫生信息研究所（Canadian Institute for Health Information, CIHI）、安大略药物福利数据库（Ontario Drug Benefit Database, ODB）、安大略省健康保险计划理赔数据库（Ontario Health Insurance Plan Claims Database, OHIP）以及加拿大器官替代登记系统（Canadian Organ Replacement Register, CORR）所维护的各类数据库。 本仓库仅包含编码列表与DIN列表，不包含个体层面数据或分析代码。数据共享协议禁止公开发布原始行政数据。如需获取ICES所持数据，可通过ICES数据与分析服务中心（https://www.ices.on.ca/DAS）提交申请。 更详细的文件说明可参见仓库根目录（codelists/）下的README.md文件。相关研究论文的补充材料中提供了变量算法（包括回溯窗口与操作定义）。 请引用该相关研究论文与本Zenodo存档记录。