crystal structure of the L136 aminotransferase from acanthamoeba polyphaga mimivirus in complex with the TDP-viosamine external aldimine

crystal structure of the L136 aminotransferase from acanthamoeba polyphaga mimivirus in complex with the TDP-viosamine external aldimine Descriptor: (2R,3R,4S,5S,6R)-3,4-DIHYDROXY-5-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)IMINO]-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL [(2R,3S,5R)-3-HYDROXY-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE, 1,2-ETHANEDIOL, CHLORIDE ION, ... Authors: Seltzner, C.A, Thoden, J.B, Holden, H.M. Deposit date: 2021-04-10 Release date: 2021-04-28 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Characterization of an aminotransferase from Acanthamoeba polyphaga Mimivirus. Protein Sci., 30, 2021

棘阿米巴原虫拟菌病毒（Acanthamoeba polyphaga Mimivirus）来源的L136氨基转移酶（aminotransferase）与TDP-紫霉胺（TDP-viosamine）外部醛亚胺（external aldimine）复合物的晶体结构。描述符：(2R,3R,4S,5S,6R)-3,4-二羟基-5-[({3-羟基-2-甲基-5-[(膦酰氧基)甲基]吡啶-4-基}甲基)亚氨基]-6-甲基四氢-2H-吡喃-2-基 [(2R,3S,5R)-3-羟基-5-(5-甲基-2,4-二氧代-3,4-二氢嘧啶-1(2H)-基)四氢呋喃-2-基]甲基二氢二磷酸酯、1,2-乙二醇（1,2-ETHANEDIOL）、氯离子（CHLORIDE ION）…… 作者：Seltzner, C.A.、Thoden, J.B.、Holden, H.M. 存放日期：2021-04-10 发布日期：2021-04-28 最后修改日期：2024-10-30 实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.95 Å） 引用文献：《棘阿米巴原虫拟菌病毒氨基转移酶的表征》，载于《Protein Science》，2021年，第30卷