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Study of human macrophage reprogramming toward a pro-resolving profile by efferocytosis

ChEBI2021-12-01 更新2026-07-12 收录

巨噬细胞编程

胞葬作用机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-8885 数据链接链接失效反馈

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资源简介：

Study of human macrophage reprogramming toward a pro-resolving profile by efferocytosis

应用场景：

创建时间：

2021-12-01

巨噬细胞编程

VISTA抗炎机制

We present the novel finding that V-domain Ig suppressor of T cell activation (VISTA) negatively regulates innate inflammation through the transcriptional and epigenetic re-programming of macrophages.

NIAID Data Ecosystem90

Single-Cell RNA Sequencing Uncovers Heterogenous Transcriptional Signatures in Macrophages during Efferocytosis

单细胞转录组学

胞葬作用机制

Efferocytosis triggers cellular reprogramming, including the induction of mRNA transcripts which encode anti-inflammatory cytokines that promote inflammation resolution. Our current understanding of t

NIAID Data Ecosystem50

The Immune Landscape of Tumor-Associated Macrophage Reprogramming.

肿瘤免疫微环境

巨噬细胞编程

Tumor-associated macrophages (TAMs) generally acquire an immunosuppressive and tumor-promoting phenotype, which may contribute to tumor resistance to immunotherapy. We previously showed that suppressi

NIAID Data Ecosystem10

Blood milieu in acute myocardial infarction reprograms human macrophages for trauma repair

心肌病免疫机制

巨噬细胞编程

Acute myocardial infarction (AMI) is accompanied by a systemic trauma response that impacts on the whole body, including blood. In this study, we addressed whether macrophages, key players in trauma r

NIAID Data Ecosystem80

Distinct Developmental Reprogramming Footprint of Macrophages During Acute Kidney Injury Across Species

急性肾损伤

巨噬细胞编程

NanoString data

NIAID Data Ecosystem20