Scn2a

ENCODES a protein that exhibits leucine zipper domain binding; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential; voltage-gated sodium channel activity; INVOLVED IN axon development; cellular response to hypoxia; cerebral cortex development; ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); autism spectrum disorder (ortholog); FOUND IN axon; axon initial segment; node of Ranvier; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2,2',5,5'-tetrachlorobiphenyl

编码一种展示亮氨酸拉链结构域结合特性的蛋白质；参与调节突触前膜电位的电压门控单原子离子通道活性；电压门控钠通道活性；涉及轴突发育；细胞对缺氧的反应；大脑皮层发育；与窒息性胸廓发育症（同源物）相关；窒息性胸廓发育症1（同源物）；自闭症谱系障碍（同源物）相关；存在于轴突；轴突起始段；朗飞结；与1-萘基异硫氰酸酯；2,2',4,4'-四溴二苯醚；2,2',5,5'-四氯联苯相互作用。