Additional file 2: Figure S1. of Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation

Number of detected CpG-sites per mean genome coverage. Figure S2. Overall CpG-site methylation levels. Figure S3. DNA methylation footprint in adipose tissue and blood. Figure S4. Invariable CpG tissue distribution and genomic feature association. Figure S5. Invariable CpG tissue distribution and genomic feature association for sites detected in â Ľ5 individuals. Figure S6. Invariable CpG tissue distribution and genomic feature association for sites detected in â Ľ10 individuals. Figure S7. Differential methylation level distribution. Figure S8. Genomic feature association of pDMCs. Figure S9. Genomic feature association of pDMRs. Figure S10. Genome feature association of DMCs of genetic vs. environmental origin. Figure S11. Proportion of eDMCs on total DMCs and eDMC genomic feature association. Figure S12. CpH methylation within sequence context. Figure S13. Overlap of methylation data with Encode blacklisted regions. Figure S14. CpG-site annotation scheme. Figure S15. pDMR definition. Additional Figure legends. (ZIP 1855 kb)