Prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase 2 (COX-2), plays a critical role in many normal physiological functions and modulates a variety of pathological conditions.

NIAID Data Ecosystem30

Genome-wide maps of KDM5A/JARID1A/RBP2 and JARID2/JMJ in HL-1 cardiomyocytes.. Mus musculus

心肌病表观遗传学

发育基因调控

We report the identification of genomic regions bound by RBP2 and JARID2 in mouse cardiomyocytes. RBP2 generates methylated lysine 4 in histone H3. Consistent with previous data, RBP2 binds at the TSS

NIAID Data Ecosystem30

DNA methylation data from pilocytic astrocytoma tumor samples and normal cerebellum controls. Homo sapiens

肿瘤表观遗传学

发育基因调控

Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating

NIAID Data Ecosystem60

Transcription profiling of Smarce1- MD (R42A) and Smarce1- MD mouse embryonic body

转录组学分析

发育基因调控

To evaluate the differential potential affected by SMARCE1 -MD/MD(R42A) , we performed RNA-sequencing (RNA-seq) of Smarce1-MD and control Smarce1-MD (R42A) embrynoic body. Overall design: we performed

NIAID Data Ecosystem30

Developmental mRNA clearance by PIWI-bound endo-siRNAs in Paramecium

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