Skin undergoes changes in structure and function with age, including a shift in metabolic programs. This is particularly evident relative to mitochondrial function in skin cells. Dermal fibroblasts ha

NIAID Data Ecosystem30

EPIC microarray of 8 keratinocyte cell strains of young and old adults

表观遗传学分析

皮肤细胞衰老

EPIC microarray of 8 keratinocyte cell strains of young and old adults

ChEBI2023-07-03 更新00

A single dose of Ultraviolet-A induces proteome remodeling and senescence in primary human keratinocytes

老化机制

皮肤细胞衰老

The UVB component of the sunlight (290-320 nm) plays an important role in carcinogenesis through generation of high levels of bipyrimidine DNA photoproducts, while UVA (320-400 nm) has been associated

NIAID Data Ecosystem40

RNAseq of Normal Human Epidermal Keratinocytes (NHEKs) in UVB-induced senescence (UVB-SIPS, at 3 days or 5 days) or in replicative-like senescence (RS)

皮肤细胞衰老

UVB诱导转录组学

RNAseq of Normal Human Epidermal Keratinocytes (NHEKs) in UVB-induced senescence (UVB-SIPS, at 3 days or 5 days) or in replicative-like senescence (RS)

ChEBI2022-12-31 更新10