Clinical characteristics and treatment received of patients included in the analysis.

Percentages are of all 9,153 patients. Extensive disease defined as AFB-smear positive, or cavities on chest x-ray if no information about AFB-smear. Prior TB therapy: defined as treatment with any, or second-line TB drugs for 1 mo or more. Later generation quinolones included levofloxacin, moxifloxacin, gatifloxacin, and sparfloxacin. Cycloserine included terizidone—a dimer of D-cycloserine given in some centers. Drugs analysed as group 5 included: amoxicillin-clavulanate, macrolides (azithromycin, roxithromycin, clarithromycin), clofazimine, thiacetazone, imipenem, linezolid, high dose INH, and thioridazine. Relapse ascertained in only 2,261 patients (14 cohorts).SD, standard deviation.