Supplementary Materials

Supplementary Fig. 1: Scatter plot for ANG on Thyrotoxicosis; Supplementary Fig. 2: Forest plot for ANG on Thyrotoxicosis; Supplementary Fig. 3: Leave-One-Out Sensitivity Analysis for ANG on Thyrotoxicosis; Supplementary Fig. 4: Funnel plot for ANG on Thyrotoxicosis; Supplementary Fig. 5: The network of protein-protein interactions (PPIs) between implicated protein targets and identified causative proteins; Supplementary Fig. 6: Results of Interaction Types in Drug-Gene Interaction Analysis; Supplementary Fig. S7: Results of Directionality in Drug-Gene Interaction Analysis; Supplementary Table. 1. Sources of Data for Mendelian Randomization Analysis in the Study; Supplementary Table. 2: Details for the SNPs related to plasma proteins; Supplementary Table. 3: Genetic instruments of Thyrotoxicosis for MR; Supplementary Table. 4: MR results for plasma proteins significantly associated with Thyrotoxicosis; Supplementary Table. 5: Results of Sensitivity Analysis for Thyrotoxicosis Pathogenic Proteins; Supplementary Table. 6: Results of Drug-Gene Interaction Analysis.补充图1：甲状腺毒症相关ANG的散点图；补充图2：甲状腺毒症相关ANG的森林图；补充图3：甲状腺毒症相关ANG的留一法敏感性分析；补充图4：甲状腺毒症相关ANG的漏斗图；补充图5：涉及的蛋白质靶点与鉴定出的致病蛋白之间的蛋白质相互作用（protein-protein interactions, PPI）网络；补充图6：药物-基因相互作用分析中的相互作用类型结果；补充图S7：药物-基因相互作用分析中的方向性结果；补充表1：本研究孟德尔随机化分析（Mendelian Randomization Analysis）的数据来源；补充表2：血浆蛋白相关单核苷酸多态性（Single Nucleotide Polymorphisms, SNPs）详情；补充表3：用于孟德尔随机化分析的甲状腺毒症遗传工具变量；补充表4：与甲状腺毒症显著相关的血浆蛋白的孟德尔随机化分析结果；补充表5：甲状腺毒症致病蛋白敏感性分析结果；补充表6：药物-基因相互作用分析结果