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Metabolite Repression and Inducer Exclusion in the Proline Utilization Gene Cluster of Aspergillus nidulans

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PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC94265/
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The clustered prnB, prnC, and prnD genes are repressed by the simultaneous presence of glucose and ammonium. A derepressed mutation inactivating a CreA-binding site acts in cis only on the permease gene (prnB) while derepression of prnD and prnC is largely the result of reversal of inducer exclusion.
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American Society for Microbiology (ASM)
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