To identify genome-wide genes regulated by direct association of AMPK to chromatin in response to energy/metabolic stress, we constructed CCRF-CEM (T-ALL) stable cell lines expressing HA-AMPKα2 and pe
Life-history theory predicts that increased investment in traits related to reproduction will be associated with a reduced ability to invest in survival or longevity. One mechanistic explanation for t
Male w1118 flies were fed for 2 days either on a 1S1Y diet or a 10S10Y diet to produce anoxia tolerant or anoxia sensitive states. Flies were then killed (columns 2 and 3) or exposed to a 1 h anoxia (
Analysis of expression patterns of various genes upregulated or downregulated during metabolic stress, including those associated with metabolism and innate immunity. (XLS 60Â kb)
Behavioral adaptations to environmental threats are crucial for survival and necessitate rapid deployment of energy reserves. The amygdala coordinates behavioral adaptations to threats, but little is