Dataset for Large gold nanoparticle release assay for attomolar detection of miRNA related to myelodysplastic neoplasms

The dataset provides relevant raw and processed Data supporting the manuscript "Large gold nanoparticle release assay for attomolar detection of miRNA related to myelodysplastic neoplasms". The manuscript is about the design of large functionalized AuNPs for attomolar detection of hsa-miR-451a using a nanoparticle release (NPR) assay and a surface plasmon resonance (SPR) biosensor.In addition, a prospective application of the developed NPR assay for the diagnosis of myelodysplastic neoplasms (MDS) is reported. Full context and detailed analysis of the provided raw and processed Data can be found in the manuscript.本数据集提供支撑研究论文《用于检测骨髓增生异常综合征相关微小RNA（microRNA，miRNA）的阿托摩尔级金纳米颗粒释放检测法》（"Large gold nanoparticle release assay for attomolar detection of miRNA related to myelodysplastic neoplasms"）的相关原始与处理后数据。该论文围绕利用纳米颗粒释放检测法（nanoparticle release assay，NPR）与表面等离子体共振（surface plasmon resonance，SPR）生物传感器，开发可实现阿托摩尔级检测hsa-miR-451a的大尺寸功能化金纳米颗粒（AuNPs）展开。此外，本研究还报道了所开发的NPR检测法在骨髓增生异常综合征（myelodysplastic neoplasms，MDS）诊断中的潜在应用。本数据集所提供的原始与处理后数据的完整背景信息及详细分析内容，均可在上述研究论文中查阅。