Additional file 1 of The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers

Additional file 1. Supplementary Tables S1-S14. Table S1: Cancer associated variants differentially mutated across tumor grade. Table S2: Co-occuring or mutually exclusive mutations in Grade1. Table S3: MutSig CV results Grade1. Table S4: Co-occuring or mutually exclusive mutations in Grade2 tumors. Table S5: MUtSig CV results Grade2. Table S6: MUtSig CV results Grade3. Table S7: Driver genes identified by MutSigCV across tumor subtypes. Table S8: MUtSig CV results IDC. Table S9: MUtSig CV results IMC. Table S10: MutSig CV results others. Table S11: MutSigCV results across Tumor stage. Table S12: MutSigCV results Ki67. Table S13: MutsigCV driver genes associated with Node status. Table S14: MutSigCV results-Ethnicity.

附加文件1：补充表S1至S14。表S1：与癌症相关且在不同肿瘤分级中突变频率存在差异的变异位点。表S2：1级肿瘤中的共突变与互斥突变。表S3：1级肿瘤的MutSig CV（Mutation Significance in Cancer）分析结果。表S4：2级肿瘤中的共突变与互斥突变。表S5：2级肿瘤的MutSig CV分析结果。表S6：3级肿瘤的MutSig CV分析结果。表S7：基于MutSig CV在各肿瘤亚型中鉴定得到的驱动基因。表S8：浸润性导管癌（IDC）的MutSig CV分析结果。表S9：浸润性小叶癌（IMC）的MutSig CV分析结果。表S10：其他样本的MutSig CV分析结果。表S11：不同肿瘤分期的MutSig CV分析结果。表S12：针对Ki67的MutSig CV分析结果。表S13：与淋巴结状态相关的MutSig CV驱动基因。表S14：基于种族特征的MutSig CV分析结果。