CCPM Freeze3 Materials and Methods

The Colorado Center for Personalized Medicine (CCPM) has recently completed a research freeze incorporating 73,346 individuals genotyped or imputed at 46,264,610 sites from 49,372 samples from whole exome sequencing (WES) and 24,079 samples genotyped on the Multi-Ethnic Genotyping Array (MEGA). We aim to describe the methods for which this research freeze was built.科罗拉多个性化医学中心（Colorado Center for Personalized Medicine, CCPM）近日完成了一项研究冻结数据集的构建，该数据集纳入了73346名个体的遗传数据：这些个体的基因型在46264610个遗传位点上完成了基因分型或基因型填充，数据来源包括49372例全外显子组测序（whole exome sequencing, WES）样本，以及24079例基于多族裔基因分型芯片（Multi-Ethnic Genotyping Array, MEGA）完成基因分型的样本。本研究旨在阐明该研究冻结数据集的构建方法。