Resolving the fibrotic niche of human liver cirrhosis at single-cell level - Seurat RData object
收藏Scottish Government Open Data Portal2019-10-25 更新2026-03-28 收录
下载链接：
https://doi.org/10.7488/ds/2637
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资源简介：
We profile the transcriptomes of non-parenchymal cell types present in healthy and cirrhotic human liver. In particular, we uncover a novel scar-associated TREM2+CD9+ macrophage subpopulation, which expands in liver fibrosis, differentiates from circulating monocytes, has a corollary population in mouse liver fibrosis and is pro-fibrogenic. We also define novel ACKR1+ and PLVAP+ endothelial cells which expand in cirrhosis, are topographically scar-restricted and enhance leucocyte transmigration.
创建时间：
2019-10-25
