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Garmultins A–G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora

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https://figshare.com/articles/dataset/Garmultins_A_G_Biogenetically_Related_Polycyclic_Acylphloroglucinols_from_Garcinia_multiflora/4219725
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资源简介:
Garmultins A and B (1 and 2), two polycyclic polyprenylated acylphloroglucinols characterized by the coupling of two novel cages, 2,11-dioxatricyclo­[4.4.1.03,9]­undecane and tricyclo­[4.3.1.03,7]­decane, along with five biogenetically related analogues (3–7), were isolated from Garcinia multiflora. Their structures and absolute configurations were determined by extensive NMR analysis, X-ray crystallography, and electronic circular dichroism calculations. Three compounds were capable of inhibiting oncogene expression and inducing apoptosis in human erythroleukemia cells.
创建时间:
2016-11-14
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