Garmultins A–G, Biogenetically Related Polycyclic Acylphloroglucinols from Garcinia multiflora
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https://figshare.com/articles/dataset/Garmultins_A_G_Biogenetically_Related_Polycyclic_Acylphloroglucinols_from_Garcinia_multiflora/4219725
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资源简介:
Garmultins A and B (1 and 2), two polycyclic
polyprenylated acylphloroglucinols characterized by the coupling of
two novel cages, 2,11-dioxatricyclo[4.4.1.03,9]undecane
and tricyclo[4.3.1.03,7]decane, along with five biogenetically
related analogues (3–7), were isolated
from Garcinia multiflora. Their structures
and absolute configurations were determined by extensive NMR analysis,
X-ray crystallography, and electronic circular dichroism calculations.
Three compounds were capable of inhibiting oncogene expression and
inducing apoptosis in human erythroleukemia cells.
创建时间:
2016-11-14



