Hypothalamic gene expression of appetite regulators in a cancer-cachectic mouse model

ChEBI2013-11-14 更新2026-07-21 收录

恶病质机制

食欲调节基因表达

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-44082 数据链接链接失效反馈

官方服务：

资源简介：

Hypothalamic gene expression of appetite regulators in a cancer-cachectic mouse model

创建时间：

2013-11-14

Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice [Tumor]. Progressive development of melanoma-induced cachexia differentially impacts organ systems in mice [Tumor]

恶病质机制

儿科肿瘤

Cachexia is a systemic wasting syndrome that develops in many cancers and increases mortality. Despite its importance, it is largely unknown how cachexia progressively and differentially induces tissu

NIAID Data Ecosystem40

Expression data from murine adipose tissue endothelial cells during pre-cachexia

恶病质机制

脂肪组织内皮细胞转录组

Endothelial cells form a barrier between the contents of the blood and adipocytes. We hypothesized that during cancer cachexia development, transcriptomic changes alter angiocrine signals to contribut

NIAID Data Ecosystem20

Kinome profiling of skeletal muscle from a mouse model of pancreatic cancer-induced cachexia

恶病质机制

激酶组学分析

More than 85% of patients with pancreatic ductal adenocarcinoma (PDAC) suffer from cachexia, a debilitating syndrome characterized by loss of muscle and fat. To model PDAC cachexia in mice, 12-week-ol

NIAID Data Ecosystem20

Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia

恶病质机制

造血微环境

Fibroblast activation protein-α (FAP) identifies stromal cells of mesenchymal origin in human cancers and chronic inflammatory lesions. In mouse models of cancer, they have been shown to be immune sup

NIAID Data Ecosystem30

Methionine cycle dysregulation mediates REDD1 overexpression-induced muscle atrophy in cancer cachexia

恶病质机制

肌肉萎缩代谢调控

The essential amino acid methionine plays a pivotal role in one-carbon metabolism, facilitating the production of S-adenosylmethionine (SAM), a critical supplier for DNA methylation and thereby a modu

Mendeley Data20

Hypothalamic gene expression of appetite regulators in a cancer-cachectic mouse model

资源简介：

相关数据集