Inducible AmpC β-Lactamase of a New Member Enterobacteriaceae

Extensive biochemical testing and 16S rRNA and rpoB sequence analysis revealed that clinical strain CF01Ent1, initially identified as Buttiauxella agrestis by the use of Api 32 biochemical strips, is a new organism in the Enterobacteriaceae family. It produced an inducible AmpC-type β-lactamase whose sequence shares 69 to 72% identity with those of the other AmpC-type β-lactamases of Enterobacteriaceae. This enzyme exhibits an atypical high affinity for all β-lactams tested.