Immunological parameters after drug withdrawal

We performed cytokine and multiplex immune profiling in drug users after withdrawal and identified the correlation between cytokines and other immune parameters. We showed that broad and strong inflammatory responses occurred at the early stage after drug withdrawal, and the inflammatory responses showed a downtrend with the extension of withdrawal time.
Excel table 1 is the basic clinical data of drug users. Excel table 2 shows the levels of 27 cytokines after withdrawal from heroin, methamphetamine and ephedrine users. Excel table 3 shows the data of complement and immunoglobulin levels after drug withdrawal. Excel table 4 is the data of immune cell level after drug withdrawal. In the excel table, M0.5 represents 7-15 days of drug withdrawal, M3 represents 3 months of drug withdrawal, and M12 represents 12 months of drug withdrawal.

本研究对戒毒后的药物成瘾者开展了细胞因子与多重免疫谱分析，明确了细胞因子与其他免疫参数之间的关联。研究发现，戒毒早期即出现广泛且强烈的炎症反应，且该炎症反应随戒毒时间延长呈下降趋势。Excel表格1收录了药物成瘾者的基础临床数据；Excel表格2展示了海洛因、甲基苯丙胺及麻黄碱成瘾者戒毒后的27种细胞因子水平；Excel表格3呈现了戒毒后补体与免疫球蛋白水平的相关数据；Excel表格4收录了戒毒后免疫细胞水平的相关数据。本数据集的Excel表格中，M0.5代表戒毒后7-15天，M3代表戒毒后3个月，M12代表戒毒后12个月。