Single-Cell Transcriptomics of Adult Recurrent Respiratory Papillomatosis

These single-cell sequencing data were generated from diseased respiratory tract papilloma tissue caused by chronic infection with HPV 6 or 11. Patients from which this tissue was derived participated in a phase I clinical trial using a novel therapeutic vaccine, but these samples were acquired before this experimental treatment. The aim of performing this single-cell sequencing study was to characterize the papilloma cells and other cells in the papilloma microenvironment with single-cell analyses using the 10X Genomics platform. The single-cell gene expression raw data files for each sample will be available in this submission. ]]> Adult patients with the clinical diagnosis of recurrent respiratory papillomatosis.]]> These papilloma samples were acquired over a one year period during standard of care papilloma removal surgery from patients with recurrent respiratory papillomatosis referred to our clinical center for evaluation and treatment. ]]>