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Citrullination of Histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma

ChEBI2016-08-03 更新2026-07-12 收录

血液肿瘤分子病理学

组蛋白修饰与细胞因子调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-80608 数据链接链接失效反馈

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Citrullination of Histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma

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创建时间：

2016-08-03

血液肿瘤分子病理学

神经发生

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy originating from plasmacytoid dendritic cells (pDCs). The microRNA expression profile of BPD

NIAID Data Ecosystem80

Molecular and transcriptional characterization of chromosome 17p loss in chronic lymphocytic leukemia

肿瘤基因组学

血液肿瘤分子病理学

Distinct genetic abnormalities such as TP53 deletion at 17p13.1, have been identified as having an adverse prognostic relevance in B-cell chronic lymphocytic leukemia (B-CLL). Conventional cytogenetic

NIAID Data Ecosystem70

Retroviral transduction of CD34+ cells with P190 and P210 BCR/ABL1 fusion genes

基因融合功能研究

血液肿瘤分子病理学

Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage The P190 and P210 BCR/A

NIAID Data Ecosystem60

Additional file 3 of IRF4 expression is low in Philadelphia negative myeloproliferative neoplasms and is associated with a worse prognosis

血液肿瘤分子病理学

基因组注释

Additional file 3: Table S2. NGS results. VCF file reporting the annotation of variants identified by NGS analysis.

NIAID Data Ecosystem80

CCL22 mutations in chronic lymphoproliferative disorder of NK cells (CLPD-NK). CCL22 mutations in chronic lymphoproliferative disorder of NK cells (CLPD-NK)

血液肿瘤分子病理学

细胞疾病模型

We engrafted empty vector, wild type CCL22, and Pro79Arg-CCL22 mutant-expressing NK-92 cells into NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(IL15)1Sz/SzJ mice to assess in vivo function of detected CCL22 mutatio

NIAID Data Ecosystem60

Citrullination of Histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma

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