Ratio of amino acid replacing (<i>K</i>a) and silent (<i>K</i>s) mutation rates for all pairwise comparisons of five tetrapod PKA Cα homologs and five primate PKA Cγ homologs.

aKa/Ks ratios for pairwise comparisons of PKA Cα from human, a prosimian primate (O. garnettii), mouse (M. musculus), cattle (B. taurus) and a frog (X. tropicalis) calculated according to the model of Goldman and Yang [89] and the model averaging method of Zhang et al. (in parenthesis) [90] for the Core16–350 sequence segment. bKa/Ks ratios for pairwise comparisons of PKA Cγ from human, chimpanzee (P. troglodytes), orangutan (P. pygmaeus), gorilla (G. gorilla) and rhesus macaque (M. mulatta) calculated as described above.