Transcriptome data

we identified bioactive components in methanol-phase extract from a traditional Chinese herbal medicine Commelina communis Linn. The bacteriostatic rate of the extract was 58% against 24 species of common pathogenic bacteria. The extract was further purified using preparative high performance liquid chromatography (Prep-HPLC) technique, and four separated componential complexes (CC) were obtained. Among these, the CC 1 significantly increased cell surface hydrophobicity, and membrane permeability, and decreased membrane fluidity, showing an action mode of damaging membrane integrity of both Gram positive and negative pathogens.