Type2_Simeonov_distr_1212_100_15_1_Counts

NIAID Data Ecosystem2026-03-11 收录

CRISPRi筛选

基因编辑模型

数据链接：

https://figshare.com/articles/dataset/Type2_Simeonov_distr_1212_100_15_1_Counts/8251439 数据链接链接失效反馈

官方服务：

资源简介：

Counts from simulated CRISPR regulatory screen. Type 2, high guide counts, low selection strength

创建时间：

2019-06-20

An Arrayed CRISPR Screen Identifies Knockout Combinations Improving Antibody Productivity in HEK293 Cells

抗体生产优化

CRISPRi筛选

Mammalian cells are used to express complex biologics, such as multispecific antibodies. While multispecifics enable promising new strategies for treating human disease, their production at high expre

NIAID Data Ecosystem30

Genome-scale CRISPRi Perturb-seq on both unstimulated and stimulated Jurkat cells reveals regulators of human T-cell signaling

T细胞信号传导调控

CRISPRi筛选

The goal of the experiment is to identify genes involved in T-cell receptor (TCR) signaling and T-cell activation in human T cells. The Jurkat E6 cell line, engineered to express dCas9-KRAB and transd

NIAID Data Ecosystem20

Human cortical organoids with engineered microglia-like cells [CROP-seq]

神经退行性疾病模型构建

CRISPRi筛选

Microglia play vital roles in the emergence and preservation of a healthy brain microenvironment with their impaired functions highlighted in neurodevelopmental and neurodegenerative disorders. Howeve

NIAID Data Ecosystem20

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Additional file 2: of CRISPRO: identification of functional protein coding sequences based on genome editing dense mutagenesis

CRISPRi筛选

功能蛋白编码序列鉴定

Table S1, Hit analysis RKO, DLD1 and NCI-H1299 cell lines (XLSX 74 kb)

Figshare2018-10-20 更新20