Numbers and 30-month percentages¹ of women with significant depression and anxiety, by randomisation arm, with odds ratios (OR) for initial colposcopy versus cytological surveillance, 95% confidence intervals (CI) and p-values (primary analysis).

1 Percentage over entire 30-month follow-up window, based on women's responses to questionnaires at 12, 18, 24 and 30 month time points. 2 Significant depression defined as score of 8 or more on HADS depression subscale. 3 Significant anxiety defined as score of 11 or more on HADS anxiety subscale. 4 Odds ratio adjusted for minimisation variables: age-group, trial centre, high-risk HPV status and eligible cytology test status. 5 Odds ratio adjusted for minimisation variables plus HADS anxiety at recruitment, HADS depression at recruitment, Carstairs' deprivation index, post-school education and training, physical activity, reproductive history, employment status, and MHLCS powerful others score. 6 Odds ratio adjusted for minimisation variables plus HADS anxiety at recruitment, HADS depression at recruitment, smoking status, marital status and employment status. 7 P-value from likelihood ratio test for dropping management arm from fully-adjusted model.