N6-Methyladenosine Methylomic Landscape of Ureteral Deficiency in Reflux Uropathy and Obstructive Uropathy

Congenital anomalies of the kidneys and urinary tracts (CAKUT) represent the most frequent cause for chronic kidney failure in children. In this dataset, we include the m6A methylated RNA data obtained from children patients with obstructive megaureter (M group) and primary vesicoureteral reflux (V group) . These data are used to obtain a total of 228 mRNAs differ btween these two diseases. Six samples were analyzed with 33700 probes. We generated the following comparisons using Fold-change (FC) ≥ 1.5 or ≤ 0.7, and p < 0.05 were used to identify the differentially m6A methylated RNAs. Two channel arrays were used for these samples but the data were analyzed as single-channel so that each sample (GSM) represents either IP or supernatent and the sample table includes the normalized signal values.