Full review data for: \"The impact of the COVID-19 pandemic on self-harm and suicidal behaviour: update of living systematic review\"

Background: The COVID-19 pandemic has caused morbidity and mortality, as well as, widespread disruption to people’s lives and livelihoods around the world. As a result of the health and economic threats posed by the pandemic to the global community, there are concerns that rates of suicide and suicidal behaviour may rise during and in its aftermath. Our living systematic review focuses on suicide prevention in relation to COVID-19, with this iteration synthesising relevant evidence up to June 7th 2020. Method: Automated daily searches feed into a web-based database with screening and data extraction functionalities. Eligibility criteria include incidence/prevalence of suicidal behaviour, exposure-outcome relationships and effects of interventions in relation to the COVID-19 pandemic. Outcomes of interest are suicide, self-harm or attempted suicide and suicidal thoughts. No restrictions are placed on language or study type, except for single-person case reports. Results: Searches identified 2070 articles. Twenty-nine articles (28 studies) met our inclusion criteria. Fourteen articles were research letters or pre-prints awaiting peer review. All articles reported observational data: twelve cross-sectional; eight case series; five modelling; and three service utilisation studies. No studies reported on changes in rates of suicidal behaviour. Case series were largely drawn from news reporting in low/middle income countries and factors associated with suicide included fear of infection, social isolation and economic concerns. Conclusions: A marked improvement in the quality of design, methods, and reporting in future studies is needed. There is thus far no clear evidence of an increase in suicide, self-harm, suicidal behaviour, or suicidal thoughts associated with the pandemic . However, suicide data are challenging to collect in real time and economic effects are evolving. Our living review will provide a regular synthesis of the most up-to-date research evidence to guide public health and clinical policy to mitigate the impact of COVID-19 on suicide. Protocol registration: PROSPERO CRD42020183326 01/05/2020

背景：新型冠状病毒肺炎（COVID-19）大流行不仅造成了大量发病与死亡病例，更对全球范围内民众的生活与生计造成了广泛冲击。鉴于此次大流行给全球社会带来的健康与经济威胁，学界担忧在疫情期间及疫后阶段，自杀及自杀相关行为的发生率可能出现上升。本动态系统综述聚焦于新型冠状病毒肺炎相关的自杀预防研究，本版综述整合了截至2020年6月7日的相关研究证据。
方法：每日自动检索结果将录入具备文献筛选与数据提取功能的网络数据库。本研究的纳入标准涵盖自杀相关行为的发生率/患病率、新型冠状病毒肺炎相关的暴露-结局关联以及干预措施的效应。本研究关注的结局指标包括自杀、自伤或自杀未遂以及自杀意念。除单人病例报告外，本研究对文献的语言类型与研究类型均无限制。
结果：本次检索共获取2070篇文献，其中29篇文献（对应28项研究）符合纳入标准。14篇文献为研究快报或待同行评议的预印本。所有纳入文献均为观察性研究，包括12项横断面研究、8项病例系列研究、5项模型研究以及3项服务利用研究。未发现任何研究探讨了自杀相关行为发生率的变化情况。病例系列研究的样本主要来自中低收入国家的新闻报道，与自杀相关的影响因素包括感染恐惧、社会隔离以及经济担忧。
结论：未来的相关研究亟需在研究设计、方法学及报告规范层面实现显著提升。截至目前，尚无明确证据表明新型冠状病毒肺炎大流行与自杀、自伤、自杀相关行为或自杀意念的增加存在关联。然而，自杀相关数据的实时收集存在较大难度，且疫情的经济影响仍在持续演变。本动态综述将定期整合最新的研究证据，为指导公共卫生与临床政策制定、减轻新型冠状病毒肺炎对自杀问题的影响提供依据。
方案注册信息：PROSPERO CRD42020183326，2020年5月1日。