In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Chemical-based external stimulation reprograms BJs into FiNs (bulk RNA-seq)

细胞重编程

转录组学分析

Here, we report that chemical-based external stimulation reprograms human BJs to generate human induced FiNs. Using transcriptome,and chromatin accessibility, we identified the cells exhibited key fe

NIAID Data Ecosystem20

Cell-type specific transcriptome and histone modification dynamics during in situ cellular reprogramming in the Arabidopsis stomatal lineage

细胞重编程

表观遗传调控

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem50

Comparison of hiPSCs, hESCs and fibroblasts

细胞重编程

基因表达谱比较分析

In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiP

NIAID Data Ecosystem50

Direct Reprogramming Human Astrocytes

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