Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand

Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand Descriptor: (3R)-N-[3-(3,4-dihydroquinolin-1(2H)-yl)propyl]-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxaline-5-carboxamide, 1,2-ETHANEDIOL, CREB-binding protein, ... Authors: Filippakopoulos, P, Picaud, S, Felletar, I, Rooney, T.P.C, Fedorov, O, Martin, S, Monteiro, O.P, Conway, S.J, von Delft, F, Brennan, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2013-12-11 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal Structure of the Bromodomain of human CREBBP in complex with a dihydroquinoxalinone ligand TO BE PUBLISHED

人类CREBBP溴结构域（Bromodomain）与二氢喹喔啉酮类配体复合物的晶体结构
描述项：配体为(3R)-N-[3-(3,4-二氢喹啉-1(2H)-基)丙基]-3-甲基-2-氧代-1,2,3,4-四氢喹喔啉-5-甲酰胺，共存组分含1,2-乙二醇（1,2-ETHANEDIOL）、CREB结合蛋白（CREB-binding protein）等
作者：Filippakopoulos, P、Picaud, S、Felletar, I、Rooney, T.P.C、Fedorov, O、Martin, S、Monteiro, O.P、Conway, S.J、von Delft, F、Brennan, P、Arrowsmith, C.H、Edwards, A.M、Bountra, C、Knapp, S，以及结构基因组学联盟（Structural Genomics Consortium, SGC）
存储日期：2013-12-11
发布日期：2014-01-29
最后修改日期：2023-09-20
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.43埃（Å）
引用信息：人类CREBBP溴结构域与二氢喹喔啉酮类配体复合物的晶体结构【待发表】