Gamma delta (γδ) T cells kill transformed cells, and increased circulating γδ T cells levels correlate with improved outcome in cancer patients; however, their function within the breast tumor microen

NIAID Data Ecosystem30

p53 deficient breast cancer cells reprogram pre-adipocytes towards tumor protective immunomodulatory cells (WEP). p53 deficient breast cancer cells reprogram pre-adipocytes towards tumor protective immunomodulatory cells (WEP)

肿瘤微环境重编程

乳腺癌免疫

The TP53 gene is mutated in approximately 30% of all breast cancer cases. Adipocytes and preadipocytes, which constitute a substantial fraction of the stroma of normal mammary tissue and of breast tum

NIAID Data Ecosystem20

Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis

内脏利什曼病风险分析

STAT信号通路

Host arginase 1 (arg1) expression is a significant contributor to the pathogenesis of progressive visceral leishmaniasis (VL), a neglected tropical disease caused by the intracellular protozoan Leishm

NIAID Data Ecosystem30

Correlations between constitutive p-STAT5, TPO induced p-STAT5, and IL6 induced p-STAT3 MFI values and disease parameters tested in circulating CD34 + cells of CALR + patients with PMF.

原发性骨髓纤维化

STAT信号通路

Correlations between constitutive p-STAT5, TPO induced p-STAT5, and IL6 induced p-STAT3 MFI values and disease parameters tested in circulating CD34+ cells of CALR+ patients with PMF.

NIAID Data Ecosystem30

EZH2-mediated epigenetic suppression of IFNa/b-STAT2 signaling enhances anti-tumor immunity in breast cancer

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