THE EFFECT OF GEOGRAPHYC AND CLIMATIC FACTORS ON THE HOSPITALITY BURDEN DUE TO KIDNEY STONES IN SPAIN 1997-2022. DATASET

Kidney stone disease (KSD) incidence is rising in the last decades becoming a worldwide problem. Besides dietary factors, climatic conditions have also been pointed out as possible reasons for explaining it. Our objective is to describe the hospitality burden due to KSD across the different regions of Spain and relate them to the different climatic conditions. METHODS: An observational retrospective study was conducted during the period 1997-2022 by analyzing hospitalization records from the minimum basic data set. Data have been related to climatic conditions (temperature, humidity, evaporation and solar radiation) collected from the Spanish meteorological agency. RESULTS: A total of 980701 hospitalizations were collected, estimating a burden of 8.4 patients per 10000 inhabitants (CI95%: 8.4-8.4) in this period. A significant increasing trend with an annual percentage change of 2.14% (CI95%: 0.9-3.4), was observed in this period. Hospitalizations were higher in men 9.6 patients per 10000 inhabitants (CI95%: 9.6-9.7) than in women (8.2, CI95%: 8.2-8.3). Humidity was the only factor that has reached a significant inverse correlation r=-0.26(CI95%: -0.26- -0.26), keeping itself as an independent factor when linear regression was applied. Temperature, radiation, and evaporation didn´t reach the statistical significance. A higher risk of hospitalizations for KSD in spring (OR: 1.1; CI95%: 1.1-1.1) has also been observed. CONCLUSIONS: Our study confirms a significant rising trend of KSD hospitalizations with significant differences across the different regions that could be partially explained by changes in the humidity values. Temperature, solar radiation or evaporation doesn´t seem to show any influence on the KSD hospitalizations.肾结石病（Kidney stone disease, KSD）的发病率在近数十年间持续攀升，已成为全球性公共卫生问题。除饮食因素外，气候条件也被认为是该病发病率上升的潜在诱因之一。 本研究旨在描述西班牙各地区KSD所致的住院负担，并探讨其与不同气候条件之间的关联。 方法：本研究为观察性回顾性研究，于1997-2022年间开展，通过分析最低基本数据集（minimum basic data set）中的住院登记数据完成。研究将上述数据与西班牙气象机构采集的气候指标（气温、湿度、蒸发量及太阳辐射）进行关联分析。 结果：本研究共纳入980701例住院病例，在此期间估算的住院负担为每10000人口8.4例患者（95%置信区间：8.4-8.4）。研究期间观察到显著的上升趋势，年百分比变化为2.14%（95%置信区间：0.9-3.4）。男性住院率更高，为每10000人口9.6例患者（95%置信区间：9.6-9.7），女性则为8.2例（95%置信区间：8.2-8.3）。 湿度是唯一达到统计学显著性的负相关因素，相关系数r=-0.26（95%置信区间：-0.26~-0.26），在线性回归分析中仍为独立影响因素。气温、太阳辐射及蒸发量均未达到统计学显著性水平。此外还观察到，春季KSD住院风险更高（优势比OR：1.1；95%置信区间：1.1-1.1）。 结论：本研究证实，KSD住院病例数呈显著上升趋势，且不同地区间存在显著差异，该差异可部分通过湿度值的变化加以解释。气温、太阳辐射及蒸发量似乎对KSD住院率无明显影响。