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Binding of electrophilic chemicals to SH(thiol)‑group of proteins and /or to seleno‑proteins involved in protection against oxidative stress during brain development leading to impairment of learning and memory

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This Adverse Outcome Pathway (AOP) describes the linkage between binding to proteins involved in protection against oxidative stress and impairment in learning and memory. Production, binding and degradation of Reactive Oxygen Radicals are tightly regulated in the body, and an imbalance between production and protection may cause oxidative stress,...

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