In the mosquito, the midgut epithelium is the initial tissue to become infected with an arthropod-borne virus (arbovirus) that has been acquired from a vertebrate host along with a viremic bloodmeal.
Effect of mutations in E2 proteins on CHIKV infectivity for Ae. aegypti mosquitoes. Exp – experiment number. N m – number of mosquitoes used to estimate OID50 value. OID50 (C95) – oral infectious dose
Mosquito-transmitted viral pathogens, such as dengue and Zika, afflict tens of thousands of people every year. These viruses are transmitted during the blood-feeding process that is required for mosqu