Vulnerability and clinical factors predicting the onset of manic symptoms as well as a (hypo)manic episode during four-year follow-up.

a = Unadjusted analyses, based on univariable multinomial logistic regression analyses.b = Adjusted analyses, based on multivariable multinomial logistic regression analyses including all variables that had p≤0.05 in the univariable analyses.c = Based on multivariable logistic regression analyses directly comparing patients developing manic symptoms with patients developing a (hypo)manic episode, including all variables that had p≤0.05 in the univariable analyses.d = For continuous variables, ORs are presented per SD increase.Vulnerability and clinical factors predicting the onset of manic symptoms as well as a (hypo)manic episode during four-year follow-up.