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l-Proline-Catalyzed Direct Intermolecular Asymmetric Aldol Reactions of 1-Phenylthiocycloalkyl Carboxaldehydes with Ketones. Easy Access to Spiro- and Fused-Cyclobutyl Tetrahydrofurans and Cyclopentanones

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NIAID Data Ecosystem2026-03-06 收录
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Acid-catalyzed ring expansion of chiral cyclopropyl and cyclobutyl derivatives for the synthesis of carbo- and heterocyclic compounds is reported. The starting materials have been successfully prepared by l-proline-catalyzed direct asymmetric aldol reactions of 1-phenylthiocycloalkyl carboxaldehydes with ketones.

创建时间:
2007-02-01
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