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Enantioselective Organocatalytic Cyclopropanation of Enals Using Benzyl Chlorides

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/Enantioselective_Organocatalytic_Cyclopropanation_of_Enals_Using_Benzyl_Chlorides/3189223
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Herein, we describe the first enantioselective cyclopropanation of enals using benzyl chlorides as bifunctional (nucleophilic and electrophilic) reagents. The reaction is simply catalyzed by chiral secondary amines to afford the formyl cyclopropane derivatives in good yields with moderate to excellent stereoselectivities.
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2016-05-02
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