Crystal structure of glycosyltransferase SgUGT94-289-3 in complex with SIA, state 1

Crystal structure of glycosyltransferase SgUGT94-289-3 in complex with SIA, state 1 Descriptor: (2S,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2S,3S,4S,5R,6S)-5-[(2S,3R,4S,5S,6S)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-6-[(3R,6S)-6-[(3S,8S,9R,10R,11S,13R,14S,17R)-3-[(2S,3R,4S,5S,6S)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,4,9,13,14-pentamethyl-11-oxidanyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-2-oxidanyl-heptan-3-yl]oxy-3,4-bis(oxidanyl)oxan-2-yl]methoxy]oxane-3,4,5-triol, URIDINE-5'-DIPHOSPHATE, glycosyltranseferease Authors: Li, M, Zhang, S, Cui, S. Deposit date: 2022-11-23 Release date: 2024-05-29 Last modified: 2024-08-14 Method: X-RAY DIFFRACTION (1.833 Å) Cite: Structural insights into the catalytic selectivity of glycosyltransferase SgUGT94-289-3 towards mogrosides. Nat Commun, 15, 2024

结合唾液酸（SIA）的糖基转移酶SgUGT94-289-3的晶体结构，状态1
描述符：(2S,3S,4S,5R,6R)-2-(羟甲基)-6-[[(2S,3S,4S,5R,6S)-5-[(2S,3R,4S,5S,6S)-6-(羟甲基)-3,4,5-三(羟基)六氢吡喃-2-基]氧基-6-[(3R,6S)-6-[(3S,8S,9R,10R,11S,13R,14S,17R)-3-[(2S,3R,4S,5S,6S)-6-(羟甲基)-3,4,5-三(羟基)六氢吡喃-2-基]氧基-4,4,9,13,14-五甲基-11-羟基-2,3,7,8,10,11,12,15,16,17-十氢-1H-环戊并[a]菲-17-基]-2-甲基-2-羟基庚-3-基]氧基-3,4-二(羟基)六氢吡喃-2-基]甲氧基]六氢吡喃-3,4,5-三醇、尿苷-5'-二磷酸（URIDINE-5'-DIPHOSPHATE）、糖基转移酶（glycosyltransferase）
作者：Li M、Zhang S、Cui S
沉积日期：2022-11-23
发布日期：2024-05-29
最后修改日期：2024-08-14
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.833埃
引用文献：《糖基转移酶SgUGT94-289-3对罗汉果苷催化选择性的结构洞察》，《自然通讯（Nature Communications，缩写Nat Commun）》，第15卷，2024年