Case Study (MOFJSSP_SDST/C)

-This real-life case study stems from the crystallization process (CP) of the 6-Ethylchenodeoxycholic acid (C26H44O4) for a pharmaceutical enterprise in Kunming, Yunnan, China. The CP is a bottleneck for the overall production efficiency as well as the quality of final products.
-There are 30 batches (i.e., jobs) of raw materials for the C26H44O4 and 5 crystallizers (i.e., machines) with different capacities and working modes. The format of this case study is briefly introduced as follows.
-First line: In the first line there are 2 numbers: the first is the number of jobs and the second the number of machines;
-Second line: the elements of the second line are the numbers of operations for 30 jobs;
-Operation processing constraints: binary numbers from lines 3 to 32 are the processing constraint associated with 30 jobs, which are in fact a partial flexibility production environment. For example, the third line “1 0 0 1 0 0 1 1 1 0 1 0 0 0 1 1 1 1 0 1 ” denotes that the first operation of job 1 can be processed by machines 1 and 4, whereas the second operation of job 1 can be processed by machines 2, 3 and 4, and so on;
-Processing times: integer numbers from lines 33 to 62 are the processing times for each operation of each job on the corresponding machines. For example, line 33 “29 -1 -1 12 -1 -1 1 44 43 -1 55 -1 -1 -1 27 94 26 91 -1 20” means that the processing times of the first operation of job 1 on machines 1 and 4 are 29 and 12 respectively, and the processing times of the second operation of job 1 on machines 2, 3 and 4 are 1, 44 and 43, and so on. Note that the “-1” denotes the related operations of certain jobs do not satisfy the processing constraints;
-Matrix of Sequence-dependent setup times;
-Matrix of Sequence-dependent setup costs.

本真实案例研究源自中国云南昆明某制药企业的6-乙基鹅去氧胆酸（6-Ethylchenodeoxycholic acid，C26H44O4）结晶工艺（Crystallization Process，CP）。该结晶工艺是制约整体生产效率与最终产品质量的瓶颈环节。
该数据集包含30批（即工件jobs）C26H44O4原材料，以及5台具备不同产能与工作模式的结晶器（即机器machines）。本案例的格式说明如下：
第一行：包含两个数值，第一个为工件总数，第二个为机器总数；
第二行：元素依次为30个工件各自的工序数量；
工序加工约束：第3行至第32行的二进制数值对应30个工件的加工约束，实际为部分柔性生产环境。例如，第3行“1 0 0 1 0 0 1 1 1 0 1 0 0 0 1 1 1 1 0 1”表示：工件1的第一道工序可由机器1和机器4加工，工件1的第二道工序可由机器2、3、4加工，依此类推；
加工时长：第33行至第62行的整数数值为各工件各工序在对应机器上的加工时长。例如，第33行“29 -1 -1 12 -1 -1 1 44 43 -1 55 -1 -1 -1 27 94 26 91 -1 20”表示：工件1的第一道工序在机器1和机器4上的加工时长分别为29和12；工件1的第二道工序在机器2、3、4上的加工时长分别为1、44和43，依此类推。注意，“-1”代表对应工件的相关工序不满足加工约束条件；
依赖序位的切换准备时长矩阵；
依赖序位的切换准备成本矩阵。