Loci with genome-significant, non-additive effects on climate adaptation and a functional analysis of nearby genes (r2>0.8) containing missense or nonsense mutations.

a,b,c,d,eLoci affecting affect multiple traits; 1The predicted functional effect score for the strongest mis-sense mutation in the gene based on amino-acid physiochemical properties (PASE) and evolutionary conservation (MSA) [40]; 2MAF: Minor Allele Frequency; 3P-value: significance after genomic-control from a linear regression analysis of squared z-scores accounting for population stratification. 4Effect: Standardized genetic effect on adaptability (Chi-square distributed) of squared z-scores accounting for population stratification; 5#Mut: number mis- and non-sense mutations in the gene in the 1001-genomes dataset [2]. 6Locus contains two missense mutations with equally strong predicted effects.Loci with genome-significant, non-additive effects on climate adaptation and a functional analysis of nearby genes (r2>0.8) containing missense or nonsense mutations.