PPI prediction data (STRING 12.0 based)

An extensive dataset of binary physical protein-protein interaction extracted from STRING 12.0 (>12,000 organisms) with artificially generated negatives. The dataset includes 72M positive pairs with STRING confidence scores> 0.9 and 720M negative pairs. The corresponding protein sequences are located in the .fasta files. The generation of the negatives was derived from https://doi.org/10.1016/j.isci.2024.110371本数据集为从STRING 12.0数据库（覆盖超12000种生物）中提取的大型二元物理型蛋白质-蛋白质相互作用（protein-protein interaction）数据集，且包含人工生成的负样本。该数据集包含7200万条STRING置信评分高于0.9的正样本对，以及7.2亿条负样本对。对应的蛋白质序列存储于.fasta格式文件中。负样本的生成方法源自以下文献：https://doi.org/10.1016/j.isci.2024.110371