IC<sub>50</sub> of RTKIs and Combinations for Parental and Resistant NSCLC cell lines.

NIAID Data Ecosystem2026-03-07 收录

数据链接：

https://figshare.com/articles/dataset/_IC_50_of_RTKIs_and_Combinations_for_Parental_and_Resistant_NSCLC_cell_lines_/841022 数据链接链接失效反馈

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IC50 of RTKIs and Combinations for Parental and Resistant NSCLC cell lines.

创建时间：

2013-11-04

EZH2 inhibition confers PIK3CA-driven lung tumors enhanced sensitivity to PI3K inhibition

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PI3K/EZH2联合靶向治疗

The purpose of this research is to study the mechanism of the synergistic effect combining EZH2 inhibition and PI3K inhibition. In this study, we observed that the PIK3CA-mutant or amplified lung canc

NIAID Data Ecosystem40

Glycoproteomic Alterations in Drug-Resistant Nonsmall Cell Lung Cancer Cells Revealed by Lectin Magnetic Nanoprobe-Based Mass Spectrometry

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Understanding the functional role of glycosylation-mediated pathogenesis requires deep characterization of glycoproteome, which remains extremely challenging due to the inherently complex nature of gl

NIAID Data Ecosystem20

Genome and transcriptome analysis of lung cancer cell lines. Genome and transcriptome analysis of lung cancer cell lines

肺癌药物敏感性

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We have used a "chemistry first" approach to discover druggable acquired vulnerabilities that arised in the pathogenesis of non-small cell lung cancer (NSCLC). We screened chemical libraries (~200,000

NIAID Data Ecosystem20

Supplementary Tables 1-6 from Inhibition of the Replication Stress Response Is a Synthetic Vulnerability in SCLC That Acts Synergistically in Combination with Cisplatin

肺癌药物敏感性

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Supplementary Table 1. Primers used for amplification of gRNA inserts. Supplementary Table 2. Raw and normalized read counts per sgRNA. Supplementary Table 3. Results from the MaGeCK analysis per gene

Figshare2019-04-01 更新30

Supplementary Tables from Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis

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合成致死靶点验证

Table S1 shows IC50 of auranofin in 129 lung cancer cell lines. Table S2 shows correlations of auranofin activity and gene expression levels (based 76 cell lines whose mRNA levels were available). Tab

NIAID Data Ecosystem20

IC<sub>50</sub> of RTKIs and Combinations for Parental and Resistant NSCLC cell lines.

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