NIHR IBD BioResource: Sample holding

The NIHR IBD BioResource comprises ~34k participants with Inflammatory Bowel Disease (IBD). The NIHR IBD BioResource acquires samples at recruitment for each participant recruited. The preferred sample collection is 3 blood tubes – see https://bioresource.nihr.ac.uk/recruiters/sample-collection-recruiters/ – from which DNA can be extracted, and plasma and sera stored. In many clinics, the NIHR BioResource blood draw follows immediately the blood collection for routine healthcare purposes. In the case of children, less blood will be taken, down to 1ml. The Technical Metadata describes the standard used by RD-Connect, the EU-wide Rare Disease biobank consortium - https://samples.rd-connect.eu/menu/main/home. During 2021, this will be replaced by an API from the UK CRC Tissue Directory, as using this discovery tool is a condition of running a Research Tissue Bank in the UK.