Organocatalyzed Enantioselective Formal [4 + 2] Cycloaddition of 2,3-Disubstituted Indole and Methyl Vinyl Ketone
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https://figshare.com/articles/dataset/Organocatalyzed_Enantioselective_Formal_4_2_Cycloaddition_of_2_3_Disubstituted_Indole_and_Methyl_Vinyl_Ketone/2513458
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资源简介：
A formal [4 + 2] cycloaddition of 2,3-disubstituted indoles with vinyl methyl ketone was realized in the presence of a catalytic amount of quinine-derived primary amine and pentafluorobenzoic acid. This method provides bridged-ring indoline scaffolds containing two quaternary carbon centers with excellent yields and enantioselectivity (up to 98% yield and 98% ee).
创建时间：
2016-02-20
