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Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

NIAID Data Ecosystem2026-03-08 收录

iPSC疾病模型

胶质瘤起始细胞靶向

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA279406 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2015-03-25

ALS疾病分子机制

iPSC疾病模型

We established iPSCs from healthy donors, FUS-ALS and SOD1-ALS patients. Using our differentiation protocol originally developed by Reinhardt et al.,2013, we diferentiated these iPSCs toward spinal mo

NIAID Data Ecosystem110

Elucidating the role of miRNA in the modulation of Survival Motor Neuron (SMN) genes in both fibroblasts and firboblast-derived iPSCs.. Elucidating the role of miRNA in the modulation of Survival Motor Neuron (SMN) genes in both fibroblasts and firboblast-derived iPSCs.

脊髓性肌萎缩症分子机制

iPSC疾病模型

Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder that affects the spinal motor neurons and leads to progressive muscle wasting and atrophy. It is caused by a reduction in SMN prot

NIAID Data Ecosystem40

Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K

iPSC疾病模型

基因突变功能分析

The PIK3CA-related overgrowth syndrome (PROS) patient-derived induced pluripotent stem cell (iPSC) lines M98-WT and M98-E418K were obtained from a female, 18-y-old PROS patient by episomal reprogrammi

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Additional file 1: of Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities

iPSC疾病模型

Zellweger谱系障碍

Characterization of candidate iPSCs. A complete listing of the protein, genetic, epigenetic, and cell differentiation assays performed on the iPSCs generated in this study is provided. (XLSX 11 kb)

Figshare2016-12-15 更新50

iPSCs derived from esophageal atresia patients reveal SOX2 dysregulation at the anterior foregut stage. Treacheophage

食管闭锁发病机制

iPSC疾病模型

The cause of esophageal atresia (EA) remains largely unknown. Differentiation to esophageal organoids of iPSCs derived from patients with EA reveals a dysregulation of SOX2 and NKX2.1, key factors in

NIAID Data Ecosystem40

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

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