Expression data from CD103+ CD11b+ cDCs expressing or not hBcl-2 transgene in the mesenteric lymph nodes under control chow diet. Expression data from CD103+ CD11b+ cDCs expressing or not hBcl-2 transgene in the mesenteric lymph nodes under control chow diet

hBcl-2 transgene under CD11c promotor fosters tolerogenic DCs properties linked to a global downmodulation of genes related to pro-inflammatory pathway and upregulation of tolerogenic ones We used microarrays to detail the global programme of gene expression underlying the tolerogenic phenotype of hBcl-2 expressing CD103+ CD11b+ cDCs to identify the pathways involved in the promotion of tolerogenic DCs ability Overall design: We performed a FACS-cell sorting of CD103+CD11b+ cDC from the mesenteric lymph nodes in both, transgenic mice expressing the hBcl-2 transgene under the CD11c promotor and control littermates (8weeks-old- under control chow diet). To obtain homogenous quantity of material, we pooled 2 to 3 samples per genotype.